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Новости Форекс

Форум будущих технологий пройдет 26 27 февраля 2026 года в Москве Индикатор

Учитывая «расходы» на синтез коллагена, где глицина используется очень много, человеку массой 70 кг нужно до десяти граммов глицина в день. Среднестатистическая диета включает около двух граммов глицина. Поэтому период полувыведения глицина составляет от получаса до четырех часов, варьируясь в зависимости от дозировки и других факторов. Включая этот рецептор, глицин влияет на транспорт через него ионов хлора и подавляет возбуждение (особенно сильно он работает в стволе мозга и спинном мозге).

Форум будущих технологий пройдет 26–27 февраля 2026 года в Москве

Зелинского РАН (Москва) синтезировали ранее не известные производные спироциклических изоксазолинов в лаборатории. Однако выделенные из губок соединения, хоть и биологически активны, сами едва ли пригодны для создания лекарственных препаратов, так как их эффективность недостаточна. Известно, что молекулы из этого класса подавляют рост золотистого стафилококка и стрептококков, вызывающих ангину, а также проявляют активность против раковых клеток. Полученные в ходе работы комплексы могут быть полезны при создании следующего поколения ярких и энергоэффективных LED-дисплеев для смартфонов и телевизоров.

  • Исследования показали, что этот класс веществ может вызывать самоуничтожение раковых клеток или дестабилизировать мембраны бактериальных клеток и подавлять в них синтез пептидов (коротких белковых молекул) и нуклеиновых кислот.
  • Химики получили такие комплексы методом кристаллизации из разных растворителей — толуола или дихлорметана.
  • «Развитие наукоемких междисциплинарных направлений, таких как биоэкономика, имеет ключевое значение в достижении технологического лидерства России – национальной цели, поставленной Президентом Владимиром Путиным.
  • Несмеянова РАН (Москва) совместно с коллегами из Физического института имени П.Н.
  • Отрасль биоэкономики подтолкнет разработку высокотехнологичных решений для множества смежных отраслей – агропромышленного комплекса, химии, ТЭК и многих других.

Растворители «настроили» цвет светящихся комплексов меди и серебра

Национальный проект «Биоэкономика» направлен на рациональное использование биологических ресурсов и применение биотехнологий в научной, технологической и экономической деятельности. Для этого необходимо объединить множество игроков, найти точки соприкосновения и оптимизировать взаимодействие между участниками рынка. Новый национальный проект призван создать условия и научную инфраструктуру для разработки прорывных биотехнологий и запустить технологические цепочки по их внедрению в экономику. «Россия обладает всей необходимой сырьевой базой, кадрами и ключевыми компетенциями для достижения целей лидерства в сфере биоэкономики.

Все-таки у глицина есть очень много эффектов на организм, порой противоположных. В целом это согласуется с результатами более свежих работ, но делать выводы и вводить метод в клиническую практику пока рановато. Кохрейновская библиотека — база данных международной некоммерческой организации «Кохрейновское сотрудничество», участвующей в разработке руководств Всемирной организации здравоохранения.

Чем нас лечат: Глицин

  • Известно, что молекулы из этого класса подавляют рост золотистого стафилококка и стрептококков, вызывающих ангину, а также проявляют активность против раковых клеток.
  • Результаты исследования, поддержанного грантом Российского научного фонда (РНФ), опубликованы в The Journal of Organic Chemistry.
  • Выходит, что Глицин отдельно — это лекарство, а с витаминами — уже добавка?

Предстоящий Форум будущих технологий объединит российских и зарубежных ученых, ведущие научные организации, крупнейших производителей, технологических лидеров в области биоэкономики и ключевые ведомства, курирующие реализацию национального проекта по обеспечению технологического лидерства по направлению «Биоэкономика», который стартует в России в 2026 году. Накопление и приумножение научно-технологического задела обеспечивает широкий спектр университетов и научных организаций, ключевые компетенции сосредоточены в НИЦ „Курчатовский институт“», – отметил вице-премьер Дмитрий Чернышенко.В рамках нацпроекта ведущие производственные компании и научные организации выступят в роли квалифицированных заказчиков и разработчиков технологий биоэкономики. В статье о борьбе с последствиями острого инсульта, по данным двойного слепого исследования на 128 пациентах, оказалось полезным подавлять действие глицина, а не усиливать его. Двойной слепой рандомизированный плацебо-контролируемый метод — способ клинического исследования лекарств, при котором испытуемые не посвящаются в важные детали проводимого исследования. В преддверии Форума будущих технологий состоится научная конференция, посвященная перспективным исследованиям в области биоэкономики. Поэтому сама возможность оказывать какое-то действие на мозг и мыслительные процессы у глицина сомнительна.

Чем нас лечат: Глицин

Иногда группе контроля дают другой препарат с уже доказанной эффективностью, а не плацебо, чтобы показать, что препарат не просто лечит лучше, чем ничего, но и превосходит аналоги. Ниже мы обсудим двойные слепые контролируемые исследования, которых среди тысяч экспериментов оказалось не так уж много. Но есть и данные в пользу того, что количество, в котором наш организм синтезирует глицин (три грамма в день) и в котором мы получаем его в с пищей (1,5-3 г), — это две трети от общей потребности. Выходит, что Глицин отдельно — это лекарство, а с витаминами — уже добавка?

Форум будущих технологий пройдет 26–27 февраля 2026 года в Москве

Поэтому ученые стремятся управлять способностью материалов изменять цвет, варьируя условия окружения. На эти параметры могут влиять температура, энергия возбуждающего света, а также химическое окружение, например, молекулы растворителя. Полученные соединения могут лечь в основу новых типов энергоэффективных материалов. Меняя окружение новых соединений, авторы добились желтой, зеленой, красной и синей эмиссии. Ученые синтезировали комплексы меди и серебра с органическими молекулами, которые испускают свет в широком диапазоне длин волн, зависящем от того, какие растворители их окружают.

Растворители «настроили» цвет светящихся комплексов меди и серебра

«Мы применили простой способ управления оптическими свойствами люминесцентных комплексов за счет изменения условий кристаллизации. Медные комплексы испускали в желтой (при использовании толуола) или красной (в случае дихлорметана) области спектра, а серебряные — в зеленой (при кристаллизации из толуола) или синей (при использовании дихлорметана). Все исследуемые комплексы проявляли люминесценцию, цвет и интенсивность которой зависели от типа металла и растворителя. Николаева СО РАН (Новосибирск) синтезировали новые люминесцентные комплексы, в которых два иона металла (медь или серебро) соединены органическими молекулами (лигандами).

Но есть и другой способ — снизить обратный захват глицина нервными клетками, чтобы как можно больше его попадало на рецепторы. В работе, где изучался эффект глицина у 22 пациентов с шизофренией или шизоаффективным расстройством, постоянный прием глицина в количестве 0,2 г/кг массы тела уменьшал негативные симптомы — состояние аффекта или отсутствие эмоций. Много интереса вызывает глицин как лекарство от шизофрении, ведь, согласно так называемой глутаматной гипотезе, галлюцинации и другие симптомы этого расстройства можно объяснить нарушением функций рецепторов NMDA. В исследовании влияния глицина на умственные способности добавка улучшала эпизодическую память и успешность выполнения заданий, где требуется концентрация внимания. От срывов при алкогольной зависимости блокирование работы глицина тоже не спасает. А вот при нейропатической боли, которая возникает из-за неправильной работы нейронов, а не из-за физического повреждения тканей, антагонист — соперник, блокирующий рецепторы глицина, — не оказал эффекта.

Правда, в составе белков глицина довольно мало (за исключением коллагена). Главный компонент Глицина — аминокислота глицин, простейшая и самая маленькая из стабильных аминокислот. Исследования показали, что этот класс веществ может вызывать самоуничтожение раковых клеток или дестабилизировать мембраны бактериальных клеток и подавлять в них синтез пептидов (коротких белковых молекул) и нуклеиновых кислот. Раньше при попытках искусственного получения эти соединения разрушались под действием сильных окислителей, которые приходилось добавлять в реакцию, чтобы «разрушить» бензольное кольцо и построить молекулы спироциклического изоксазолина.

Оргкомитет Форума будущих технологий определил даты и место проведения четвертого Форума – 26–27 февраля 2026 года в Центре международной торговли в Москве. О своих исследованиях сообщайте на нашу почту. Вероятность, что действие все же существует, есть, хоть и очень мала. Ждать от него каких-то лекарственных свойств и тем более ноотропных чудес не следует.

Чем нас лечат: Глицин

Но кроме этого, глицин участвует в синтезе порфиринов (среди этих веществ — гем, который держит кислород в гемоглобине) и работает нейромедиатором. В организме он, конечно, может разными путями разрушаться, но по умолчанию аминокислота — это уже строительный «кирпичик» для сборки любых белков. Кроме того, такой метод легко масштабируем, благодаря чему он позволит получать большие количества спироциклических изоксазолинов для расширенных биологических испытаний, которые помогут лучше понять механизм противоопухолевого и антимикробного действия этих соединений. Исследователи предложили метод, при котором мягким окислителем выступает нитрогруппа, уже содержащаяся в соединении-предшественнике.

Несмотря на то что Глицин в России зарегистрирован и продается как медицинский препарат, в реальности это обычная аминокислота, которую мы не только получаем с пищей, но и сами умеем синтезировать в организме. По результатам лекарство признали безопасным и снижающим негативные симптомы шизофрении. Этим путем пошли авторы исследования 2016 года, где поучаствовало уже больше 100 пациентов (а длились испытания 52 недели). Пациентам назначали пищевую добавку — глицин вместе с другой аминокислотой, триптофаном. Здесь глицин (в дозировке 0,8 г на килограмм массы тела) исследуется как средство от симптомов психоза.

Разница между ними и медикаментами состоит в том, что для биодобавок не предусмотрены клинические исследования, а значит, эффективность их применения не имеет доказательств». К тому же это в России Глицин — лекарство, в США, к примеру, он всего лишь БАД. «Глицин — это аминокислота, которая действительно участвует в передаче импульсов между нервными клетками. Однако в этом случае глицин, наоборот, участвует в процессах возбуждения, а не торможения. Также аминокислота участвует и в работе рецептора NMDA — то есть помогает глутамату, который сам не справляется, «открыть ворота» для потока ионов. Кстати, именно это действие нейтрализуется кофеином, который не просто бодрит нас, а не дает затормаживаться.

Отрасль биоэкономики подтолкнет разработку высокотехнологичных решений для множества смежных отраслей – агропромышленного комплекса, химии, ТЭК и многих других. «Развитие наукоемких междисциплинарных направлений, таких как биоэкономика, имеет ключевое значение в достижении технологического лидерства России – национальной цели, поставленной Президентом Владимиром Путиным. Предусмотрено создание центров пилотирования и масштабирования продукции биоэкономики, центров подготовки кадров, проведение научных исследований, продвижение российских продуктов биоэкономики на зарубежных рынках, внедрение цифровых решений и отечественного ПО на производствах и другие меры поддержки отрасли. Нацпроект предусматривает меры по развитию и внедрению биотехнологий в агропромышленном комплексе, ветеринарии, промышленности, экологии, лесопромышленном комплексе, медицине и энергетике.

Японские ученые попробовали применять глицин против гиперурикемии (повышенного содержания мочевой кислоты в крови). Правда, хоть упоминаний глицина в PubMed тысячи, среди них практически нет его клинических испытаний в качестве лекарства. Допустим, от этого мы убедимся, что стоило бы есть побольше глицина.

Результаты исследования, поддержанного грантом Российского научного фонда (РНФ), опубликованы в журнале Inorganic Chemistry Communications. В рамках Форума состоится традиционная выставка, на которой лидеры рынка, наукоемкие предприятия и научные организации представят передовые разработки и новейшие инновационные решения в сфере биоэкономики. Все это при разработке комплекса мер по продвижению сбыта и экспорта продукции биоэкономики обеспечит лидерство России в этой отрасли», – прокомментировал руководитель национального проекта «Биоэкономика», Министр промышленности и торговли Российской Федерации Антон Алиханов. В соответствии с поручением Президента Российской Федерации Владимира Путина Форум будет посвящен формированию биоэкономики в Российской Федерации и применению биотехнологий в отраслях экономики.

Растворители «настроили» цвет светящихся комплексов меди и серебра

Это, в свою очередь, делает спироциклические изоксазолины перспективными для создания новых лекарственных препаратов. Поэтому нужны медикаменты на основе новых молекулярных структур, например морских метаболитов — биологических веществ с высокой активностью, к которым относятся морские алкалоиды, оказывающие противомикробное и противоопухолевое действие, но еще широко не используемые в фармацевтике. Результаты исследования, поддержанного грантом Российского научного фонда (РНФ), опубликованы в The Journal of Organic Chemistry. Полученные вещества могут служить структурной основой при создании новых лекарственных препаратов, в первую очередь, противомикробного и противоракового действия. Химики получили такие комплексы методом кристаллизации из разных растворителей — толуола или дихлорметана. Несмеянова РАН (Москва) совместно с коллегами из Физического института имени П.Н.

На группе всего из 22 пациентов получены данные, что глициновая пудра лучше бикарбоната натрия борется с бактериальным налетом в ротовой полости, но надо дополнительно изучить этот метод, подтверждая его безопасность и действие на выборках побольше. У него есть и свой персональный рецептор, глициновый, который, однако, особой верности ему не хранит и не прочь активироваться и другими простейшими аминокислотами. Кроме того, мы исследуем влияние природы растворителя на их люминесцентные свойства», — рассказывает участник проекта, поддержанного грантом РНФ, Арина Ольбрых, сотрудник лаборатории гидридов металлов Института элементоорганических соединений имени А.Н. Цель нацпроекта – достижение к 2030 году технологического суверенитета в биоэкономике посредством сокращения в 2 раза импортозависимости, а к 2036 году – создание условий для формирования новых рынков и технологического лидерства. Диалог участников отрасли на Форуме будущих технологий в феврале будет направлен на координацию мер по реализации нацпроекта», – сказал ответственный секретарь Оргкомитета по подготовке и проведению Форума будущих технологий, советник Президента Российской Федерации Антон Кобяков.

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Vicibet

Showboat Branson Belle 2026 Schedule & Tickets

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The Captain’s Row seating offers unmatched viewing of the show with premium menu options to choose from as well! The most popular choice, these tickets provide you with a great view of the show and the delicious meal that is served along with it. Valued at $29.95, this card and booklet offers you nearly $5,000 in deals and discounts around Branson!

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Rihanna “Popstar” Biography, Age, Husband and Children

The record also featured the popular power ballad “Unfaithful,” as well as singles “We Ride” and “Break It Off.” The album debuted at No. 5 on the Billboard 200 chart and earned her first No. 1 hit with the catchy pop single “SOS,” which spent three weeks atop Billboard’s Hot 100. In 2008, Rihanna topped the chart three times, twice with her own songs “Disturbia” and “Take a Bow,” plus a feature on T.I.’s “Live Your Life.” She has also earned nine number-one songs on the UK Singles Chart and ranks second to the Beatles for the most million-selling singles in the country. This made her the artist with the most digital single awards and the first performer to exceed RIAA’s 100 million cumulative singles certification threshold. With estimated worldwide sales exceeding 250 million records as of 2023, Rihanna is one of the best-selling music artists of all time.

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  • Her work has influenced artists such as Lorde, Sam Smith, Billie Eilish, Selena Gomez, Ed Sheeran, Ellie Goulding, Kim Petras, Marilyn Manson, Jessie J, SZA, Ayra Starr, and Demi Lovato.
  • Rihanna is one of the best-selling music artists of all time, with estimated sales of over 250 million records.
  • Reuniting with her pop powerhouse collaborators Max Martin and Shellback, who worked on her biggest pop radio hits like “We Are Never Ever Getting Back Together,” “Delicate,” “Blank Space,” and “Shake It Off,” was a return to form after the fog of TTPD.
  • “SOS” became her first song to reach number one on the Billboard Hot 100, while “Unfaithful” was a top-ten single worldwide.
  • Yet the song made its way to the States, where it found popularity in New York, New Jersey and Connecticut’s Caribbean diaspora and caught the ear of hip-hop innovators of the ’80s.
  • Fans rejoiced at having songs to comfort them during difficult times, and artists like Maya Hawke, Gracie Abrams, and Sabrina Carpenter credit folklore for inspiring them to create and be even more emotionally honest in their songwriting.
  • In 2007, Rihanna transformed from a teen pop star into a serious artist with her groundbreaking album “Good Girl Gone Bad,” which featured the iconic single “Umbrella,” featuring Jay-Z.

As Swift revealed on May 30, she bought back the master recordings of her first six albums, marking the first time she’s been in control of her entire discography. Throughout a total of 31 tracks, the prolific songwriter shelved the glittery pop radio-friendly tunes in favor of more subdued, synthy and heart-wrenching songs. Midnights helped further solidify Swift’s larger-than-life status at the finale of the 2024 GRAMMYs, too, as she became the only artist in history to win Album Of The Year four times. Along with breaking several streaming records — including becoming the first album to exceed 700 million global streams in a week — it was Swift’s 11th No. 1 debut on the Billboard 200, and was the highest-selling album of 2022 (and, remarkably, the second best-selling of 2023).
Although Jay-Z initially thought “Pon de Replay” was too big for a new artist, he invited her to audition. Rihanna’s demo was sent to rapper Jay-Z, who had just become the president and CEO of the record label Def Jam Recordings. In 2005, she became the first artist to sign with Syndicated Rhythm Productions, the production company founded by Rogers and Carl Sturken. Unnamed and without original material, the girl group auditioned for American producer Evan Rogers, who recalled that “the minute Rihanna walked into the room, it was like the other two girls didn’t exist”. Though she initially planned to finish high school, she ultimately dropped out at age 16 to pursue a music career. Signed to Def Jam Recordings, she debuted with the Caribbean-inspired records Music of the Sun (2005) and A Girl Like Me (2006), both of which reached the top ten of the US Billboard 200.

Images

The line debuted in a Paris pop-up on May 22 before a worldwide online release seven days later, featuring clothing, accessories, and footwear. It included an array of products including foundations, highlighters, bronzers, blush compacts, lip glosses, and blotting sheets, and was praised for offering shades that catered to all skin tones. The $10 million partnership produced a wide range of beauty products, with the first collection released on September 8, 2017, in stores and online across more than 150 countries. Over the next two years, she released a variety of footwear in different styles and colourways, all receiving positive responses from critics and consumers alike. Rihanna went on to collaborate with numerous fashion houses, including Dior, Stance, and Manolo Blahnik. She also established a photography agency, A Dog Ate My Homework, representing photographers Erik Asla and Deborah Anderson.

  • The doo-wop-infused ballad soared to No. 5 on the Billboard Hot 100 back in 2017, and its new certification helps Rihanna extend her record as the female artist with the most Diamond singles in RIAA history.
  • Despite its ghoulish title, artificial intelligence appears to be the object of terror in what many, including the GRAMMY voters who awarded it Best Pop Duo/Group Performance in 2024, regard as the highlight of SZA’s sophomore.
  • Gleefully playing the witch doctor, prolific singer/bassist Esperanza Spalding individually released every song (and an accompanying video) from her seventh album across 11 days before serving up its cauldron of genre-hopping sounds in full.
  • In 2014, Shakira featured Rihanna on her single “Can’t Remember to Forget You”.
  • The pair meet and fall in love on the Titanic, the greatest ship to sail the oceans.
  • Subsequently, Rihanna held the No. 1 spots on the Billboard 200 and Hot 100 simultaneously, her second time achieving such an impressive feat.

Swift also found a new sense of creativity within this new mindset, one where she aimed to still embed playful themes in her songwriting but with less snark than that of “Blank Space” and “Look What You Made Me Do.” Leaning into Lover being a “love letter to love,” Swift explored every aspect of it. After finding love amongst chaos with reputation, Swift was learning to deal with the anxiety and fear of losing her partner — became a major theme of another aptly titled album, Lover. With time, though, it became clear that the response to reputation became muddled with the public’s overall perception of her at the time — some even claimed that Swift was ahead of her time with the album’s overall sound. Although Swift said that the album has its vindictive moments — even declaring that the “old Taylor” is dead on the bridge of “Look What You Made Me Do” — it’s a vulnerable record for her. Following the release of 1989, Swift became a cultural juggernaut, and the album has had an omnipresence in music since. And where some might trade a hit or two at the expense of their artistic integrity, Swift didn’t falter — instead, her lyrics were just as heartfelt and intimate as they were on prior albums.

Rihanna debuts new baby bump at Met Gala

Gleefully playing the witch doctor, prolific singer/bassist Esperanza Spalding individually released every song (and an accompanying video) betista casino from her seventh album across 11 days before serving up its cauldron of genre-hopping sounds in full. (Rih recorded an equally moving sequel for her Loud album.) Three years later, the two confronted their inner demons in “The Monster,” and their musical chemistry scored a GRAMMY in 2015 for Best Rap/Sung Collaboration. Final single “Te Amo” didn’t chart, but garnered a great deal of attention as the Latin-infused Stargate production depicts Rihanna being enticed by a female love interest. It also marked Rihanna’s first time veering away from her “girl next door” image, as the song’s subject matter deals with infidelity. Follow-up single “If It’s Lovin’ That You Want” stalled at No. 36 on the Hot 100, but still whetted fans’ appetite — as did her debut album, Music of the Sun, which is mostly comprised of dance-pop and dancehall tracks with hints of R&B (like “Willing to Wait”). Shortly after her 16th birthday, Rihanna left her home country for the U.S. to record a demo, which included her breakthrough hit “Pon de Replay.” The demo found its way into Jay-Z’s hands, and Hov signed the teen artist to Def Jam and the label expedited her 2005 debut album, aptly titled Music of the Sun.
Following the release of Unapologetic and the ensuing tour, she expressed a desire to take a break from recording, saying she wanted “a year to just do whatever I want artistically, creatively”. That same month, the Official Charts Company reported she had sold 3.87 million records in the country over the past year, placing her at number one among the 2013 Brit Awards artist nominees. Rihanna’s seventh studio album, titled Unapologetic, was released on November 19, 2012. A dance-oriented pop and R&B album, Talk That Talk opened at number three on the US Billboard 200 with first-week sales of 198,000 copies, while debuting atop the UK Albums Chart with 163,000 units sold. Rihanna aimed to explore more sexually expressive themes on her sixth studio album, Talk That Talk, which was released on November 18, 2011. A dance-pop record, Loud debuted at number three in the US with first-week sales of 207,000 copies.
Retrospective and reflective, Speak Now is an album about the speeches she could’ve, would’ve and should’ve said. The album’s title track pulled from the saying, “Speak now or forever hold your peace,” inspired by a friend’s ex-boyfriend getting engaged; meanwhile, “Mean” was everything Swift wanted to say to a critic who was continuously harsh about her vocals. Along with having more eyes on her, Swift also felt pressured to maintain her persona as a perfect young female role model amid a time when her peers like Miley Cyrus and Demi Lovato were attempting to rebrand to be more mature and sexier. But this meant that she faced more publicity and criticism, from naysayers who nitpicked her songwriting and vocals to the infamous Kanye West incident at the 2009 MTV Video Music Awards.

Rihanna and A$AP snuggle up leaving Cannes carpet

Elizabeth Taylor has appeared as a character in Swift’s songs before, particularly in rep’s “Ready For It…?” where she compares herself to the famous actress and entertainer. Comparatively, “Eldest Daughter” — track five, a spot Swift notoriously reserves for the most emotional song — is a love song about the masks we wear and the selves we choose to reveal. Throughout the record, dynamic and layered pop soundscapes mimic the same energy Swift was feeling both on and off stage. “I thought who better to ask to be a part of this song than the ultimate showgirl Sabrina Carpenter.” Instead of writing songs akin to “I Can Do It With A Broken Heart,” a song about performing in the midst of heartbreak and grief, Swift opted to focus on what people don’t necessarily see when they buy a ticket to a show. Now that the curtain is up and The Life of a Showgirl is out, read on for five key essential insights from Taylor Swift’s new album.

Instead, she wanted to capture the years of her life while they still represented what she was going through, writing about what she was observing and experiencing, from love and friendship to feeling like an outsider. Written throughout her adolescence, Taylor Swift was recorded at the end of 2005 and finalized by the time Swift finished her freshman year of high school. In a genre dominated by men, the odds were already stacked against Swift when she first broke into country music as a teenage female artist.
Rihanna, who has not released a full album since 2016’s “Anti,” voices Smurfette in the film. The songstress herself shared a sweet note on Friday, Aug. 29, thanking her fans and those who “gave me a chance over the years.” To celebrate her success in the music business and beyond, Rihanna is releasing “R20” merch and a vinyl album boxed set, which are available for pre-order on her official online store.
She first gained prominence in 2005 with her debut album “Music of the Sun,” which quickly established her as a force in the music industry. Known for her unique style and chart-topping hits, she has influenced music and fashion worldwide. She told Winfrey that Brown may have been the love of her life and she has developed “a very close friendship” with him. The pair worked together on the song “Birthday Cake,” released that year.
Swift opted to lean more into radio-friendly hits, which resulted in songs like “Style,” “Wildest Dreams,” “Blank Space,” and “Shake It Off,” all of which became singles. Often mentioned as a record that inspired a generation of artists from Troye Sivan to Conan Gray, Swift’s confessional, soul-bearing authenticity set a new standard for straightforward pop music. Much like her previous two albums, Swift included songs that were both inspired by her own life and being a fly on the wall. During her NYU commencement speech in 2022, she reflected on this era of her life as one of intense fear that she could make a mistake and face lasting consequences, so the songs were masked in metaphors rather than directly addressing adult themes in her music. Serving as a snapshot of Swift’s life and teenhood, she avoided songwriting stereotypes typically found in country music.
Following the success with folklore and evermore, Swift’s intrigue was at a then-all-time high upon the release of Midnights. Although the album is a departure from the two pandemic sister albums, the overall creation process didn’t differ too much. On Midnights, Swift leaves behind indie folk sounds and returns to the pop production of 1989 and Lover. After coming out of the folklorian woods following folklore and evermore, fans and critics alike were intrigued to see what direction Swift would take on her next studio album. Even so, its poetic lyricism and mystical storytelling cleverly foreshadowed what was to come with subsequent albums, particularly The Tortured Poets Department.
Swift still remained in the pop lane with reputation, largely leaning on Antonoff and the Martin/Shellback team. She stayed away from public appearances, didn’t do any press, and missed the album schedule fans became accustomed to. For years, Swift was on a strict two-year cycle — she’d release an album one year, tour the next, and then release a new album the following year. In turn, Billie Eilish, Dua Lipa and more pop stars have refused to conform or stick to what they’ve done prior.
Its win for Best Urban Contemporary Album at the 2014 GRAMMYs, however, proved that Rihanna’s reign wasn’t letting up anytime soon. “Mr. Jesus, I’d love to be a queen/ But I’m from the left side of an island/ Never thought this many people would even know my name,” she pleads in the seven-minute two-parter. Her swagger is boisterous in “Phresh Out the Runway,” “Jump,” and strip club anthem “Pour It Up,” but “Nobody’s Business” really drives home the album’s theme of being unbothered. Vocally, Rihanna’s strength lies in her ability to evoke raw emotion à la “Stay.” Featuring Mikky Ekko, the stripped-down, slow-burning piano ballad narrowly missed the top spot on the Hot 100 but gave Rihanna her 24th top 10 hit, surpassing Whitney Houston’s record of 23 in 2013. One of Rihanna’s most precious offerings to date, “Diamonds” emerged as a self-love mantra due to its uplifting “Shine bright like a diamond” chant. Its lead single “Diamonds” resonated in an equally major way, giving Rih her 12th No. 1 on the Hot 100.
The thing that differentiated her from other writers — and still does to this day — is her songwriting. The world now knows Taylor Swift as a global pop superstar, but back in 2006, she was just a doe-eyed country prodigy. Despite its ghoulish title, artificial intelligence appears to be the object of terror in what many, including the GRAMMY voters who awarded it Best Pop Duo/Group Performance in 2024, regard as the highlight of SZA’s sophomore. But four years after the Team Edward vs Team Jacob saga wrapped up, folk hero Jason Isbell proved mythical bloodsuckers weren’t a barrier to awards success. David Bowie fans may well feel aggrieved that his post-punk classic “Scary Monsters (and Super Creeps)” was entirely ignored by GRAMMY voters, while the bro-step banger it inspired was showered with awards. It’s a bold feminist act that helped power parent album CrazySexyCool to diamond status and was deservedly rewarded with Best R&B Performance By A Duo Or Group With Vocal at the 1996 GRAMMYS (where CrazySexyCool was also crowned Best R&B Album).

The Life of a Showgirl: Offering A Peek Behind The Curtain

Rihanna also said that Carey’s “Vision of Love” (1990) was the song that inspired her to pursue a career in music. Vulnerability is explored on the pop and synth-pop record Unapologetic (2012), which Vulture described as an “act of defiance … to sort out her feelings about her … ex-boyfriend Brown and her public image”. Rihanna’s rock-imbued record Rated R (2009), released after the assault by her then-boyfriend, Chris Brown, had a much darker tone and was filled with various emotions she experienced since then.
Rihanna became the youngest and fastest solo artist in Billboard Hot 100 history to accumulate ten number-one singles. In late 2008, she released “Rehab”, the fifth and final single from Good Girl Gone Bad; it peaked within the top 20 of the charts in both the US and UK. The following singles, “Shut Up and Drive” and “Hate That I Love You”, saw moderate success, while the album’s fourth single, “Don’t Stop the Music”, peaked at number three in the US.
Rihanna has faced personal challenges, including a highly publicized incident of domestic violence with former boyfriend Chris Brown. With these endeavors combined with her musical empire, Rihanna has not only cemented her legacy in music but also positioned herself as a powerful icon in the world of entrepreneurship. The singer launched her makeup line, Fenty Beauty, in 2017, gaining instant popularity for its extensive range of shades catering to all skin tones. This wealth is a result of her multifaceted career, which extends beyond music to include ventures in fashion, beauty, and film. Rihanna, one of the most successful pop stars of her generation, has amassed an impressive net worth estimated to be around $1.7 billion, according to Forbes. Rihanna’s romantic life has often made headlines, with notable relationships sparking both admiration and intrigue.

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Bookkeeping

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CFI is the global institution behind the financial modeling and valuation analyst FMVA® Designation. CFI is on a mission to enable anyone to be a great financial analyst and have a great career path. In order to help you advance your career, CFI has compiled many resources to assist you along the path. There are a few different methods for calculating net working capital, depending on what an analyst wants to include or exclude from the value. To reiterate, a positive NWC value is perceived favorably, whereas a negative NWC presents a potential risk of near-term insolvency.

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If your NWC isn’t where you want it to be – or you’re just trying to strengthen your financial position – consider adjusting your pricing strategy, speeding up your accounts receivable, or negotiating longer terms with suppliers. Sometimes, you can do it by refining your inventory management so you don’t tie up too much cash in unsold goods. If your current assets total $100,000 and your current liabilities add up to $70,000, your NWC is $30,000. That means you’ve got $30,000 leftover to cover your day-to-day costs once all the short-term liabilities are met. An increasing ratio indicates that your business is reducing its investments in fixed assets. Also, such businesses make payments toward outstanding expenses using cash.

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Onе crucial mеtric that providеs insights into nwc meaning a company’s short-tеrm liquidity and opеrational еfficiеncy is Nеt Working Capital (NWC). NWC is a financial bеacon, offеring a snapshot of a company’s ability to mееt its short-tеrm obligations and fund its day-to- day opеrations. For example, if Company ABC has current assets of £120,000 and current liabilities of £90,000, then the net working capital would be £30,000.

nwc meaning

Most businesses use the standard net working capital formula in general practice, but knowing how to alter the formulas based on what measures you’re analyzing can be helpful, too. A couple more examples of this are the net working capital requirement and net working capital ratio. Calculating net working capital isn’t difficult once it’s clear what is being factored into the calculations. Essentially, net working capital is concerned with short-term assets and liabilities, which mean those that will be paid or come due within one year.

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Therefore, you need to check the credit score of your customers before entering into any sort of agreement with them. As mentioned above, a shortfall in the Net Working capital can have a negative impact on your business. However, you may assume that taking a loan or using a credit line are the ways by which you can resolve the challenge of the inadequacy of the Net Working Capital. Your business must maintain a sound Net Working Capital to run its business operations. Both excessive and inadequate Net Working Capital positions impact your business. Adequate Net Working Capital ensures that your business has a smooth operating cycle.

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A vice-versa or negative working capital shows that the company will face financial problems in settling its current liabilities. It shows that the business holds its inventory for a long time, i.e., taking time to sell them, and also that the business is Balancing off Accounts holding extra cash which should be invested or used in its expansion. It isn’t easy to decide how much working capital is enough for a business to flourish.

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nwc meaning

If either sales or COGS is unavailable, the “days” metrics cannot be calculated. When this happens, it may be easier to calculate accounts receivables, inventory, and accounts payables by analyzing the past trend and estimating a future https://ncp.vn/free-freelance-invoice-templates-sage-advice-us/ value. Create subtotals for total non-cash current assets and total non-debt current liabilities. Subtract the latter from the former to create a final total for net working capital. If the following will be valuable, create another line to calculate the increase or decrease of net working capital in the current period from the previous period. However, the more practical metric is net working capital (NWC), which excludes any non-operating current assets and non-operating current liabilities.

Since the two terms are the same, they will be used interchangeably in the article. Since the company is holding off on issuing payments, the increase in payables and accrued expenses tends to be perceived positively. In the final part of our exercise, we’ll calculate how the company’s net working capital (NWC) impacted its free cash flow (FCF), which is determined by the change in NWC. Net working capital, often abbreviated as “NWC”, is a financial metric used to evaluate a company’s near-term liquidity risk. Investing more money in inventory means keeping your cash idle and not putting it to use. Therefore, this results in decreased liquidity and makes your business less competitive.

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However, such techniques do not play a significant role in managing your current assets. It is important to understand that short-term debts constitute liabilities in the calculation of the working capital. This is because long-term debts are expected to be paid off over a longer period of time with no immediate cut into the assets.

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Also in 1993, Craig was featured in two episodes of the American television shows Zorro and George Lucas’s The Young Indiana Jones Chronicles, and British shows Heartbeat, in which he played Peter Begg; Between the Lines; Drop the Dead Donkey and Sharpe’s Eagle. Having played minor roles in the miniseries Anglo-Saxon Attitudes and the shows Covington Cross and Boon, he appeared in November 1993 as Joe in the Royal National Theatre’s production of Tony Kushner’s Angels in America. Craig appeared in his first screen role in 1992, playing an Afrikaner in The Power of One. At the age of 14 in 1982, he played roles in Romeo and Juliet and Cinderella at Hilbre High School. In 2006, Craig played Bond in Casino Royale, a reboot of the Bond franchise that was favourably received by critics and for which Craig was nominated for the BAFTA Award for Best Actor in a Leading Role.

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In 1984, he was accepted into the National Youth Theatre and moved to London, where he worked part-time in restaurants to finance his education. Craig began acting in school plays at the age of six, making his debut in the Frodsham Primary School production of Oliver! He made his Broadway debut in the play A Steady Rain (2009) and returned to Broadway in the revivals of Harold Pinter’s Betrayal (2011) and William Shakespeare’s Macbeth (2022). On stage, Craig starred in the Royal National Theatre’s production of Angels in America (1993) on the West End. Don’t hesitate to get in touch – we’re here to ensure your registration experience is smooth and hassle-free. Simply navigate to our website using your mobile browser or download our PWA app, choose a currency, deposit funds, and complete the KYC upload.

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In 2004, Craig first met longtime Bond co-producer Barbara Broccoli at the funeral of casting director Mary Selway, who had cast Craig in Love Is the Devil. He then appeared briefly in the Hungarian film Fateless as a United States Army Sergeant who takes a liking to a teenage boy who survives life in concentration camps. Kevin Crust, writing for the Los Angeles Times, praised Craig’s “stunningly suave performance”, while Roger Ebert thought he was “fascinating” in the film. In 2001, Craig also starred in the four-part Channel 4 drama Sword of Honour, based on the trilogy of novels of the same.
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